ADAMTS13 (Human) Recombinant Protein (P01)
产品名称: ADAMTS13 (Human) Recombinant Protein (P01)
英文名称: ADAMTS13 (Human) Recombinant Protein (P01)
产品编号: H00011093-P01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
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 - 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
 - 邮编 : 11493
 - 所在区域 : 台湾
 - 电话 : +886-920**1152 点击查看
 - 传真 : 点击查看
 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Human ADAMTS13 full-length ORF ( AAH39251.1, 1 a.a. - 75 a.a.) recombinant protein with GST-tag at N-terminal.
 
- Sequence:
 - MQLFGPWGEIVSPSLSPATSNAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILVRPSMGTCAVILDSFP
 
- Theoretical MW (kDa):
 - 34.1
 
- Preparation Method:
 - in vitro wheat germ expression system
 
- Purification:
 - Glutathione Sepharose 4 Fast Flow
 
- Storage Buffer:
 - 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
 
- Storage Instruction:
 - Store at -80°C. Aliquot to avoid repeated freezing and thawing.
 
- Quality Control Testing:
 - 12.5% SDS-PAGE Stained with Coomassie Blue.

 
- Note:
 - Best use within three months from the date of receipt of this protein.
 
- MSDS:
 
Download
- Application Image
 
- Enzyme-linked Immunoabsorbent Assay
 
- Western Blot (Recombinant protein)
 
- Antibody Production
 
- Protein Array
 
- Entrez GeneID:
 - 11093
 
- GeneBank Accession#:
 - BC039251.1
 
- Protein Accession#:
 - AAH39251.1
 
- Gene Name:
 - ADAMTS13
 
- Gene Alias:
 - C9orf8,DKFZp434C2322,FLJ42993,MGC118899,MGC118900,TTP,VWFCP,vWF-CP
 
- Gene Description:
 - ADAM metallopeptidase with thrombospondin type 1 motif, 13
 
- Gene Ontology:
 - Hyperlink
 
- Gene Summary:
 - This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq
 
- Other Designations:
 - OTTHUMP00000022496,OTTHUMP00000022497,OTTHUMP00000022498,a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13,vWF-cleaving protease,von Willebrand factor-cleaving protease
 
- Related Disease
 
- Atherosclerosis
 - Brain Ischemia
 - Cardiovascular Diseases
 - Cerebrovascular Accident
 - Chronic Disease
 - Coronary Disease
 - Genetic Predisposition to Disease
 - Inflammation
 - Myocardial Infarction
 - Obesity
 - Ovarian Failure, Premature
 - Peripheral Vascular Diseases
 - Polycystic Ovary Syndrome
 - Pregnancy Complications, Hematologic
 - Puberty, Delayed
 - Puberty, Precocious
 - Purpura, Thrombotic Thrombocytopenic
 - Stroke
 - Thrombophilia
 
